One person was seriously injured in a collision involving a pick-up truck and an SUV in Mecca.
It happened shortly after 6:30 p.m. Saturday at the intersection of Avenue 70 and Cleveland Street.
Cal Fire said 5 people were taken to hospitals for treatment.
Two people suffered moderate injuries.
The California Highway Patrol said a motorist in a gray Dodge Ram was speeding before the vehicle crashed into a Chevy Tahoe.
One person was airlifted to Desert Regional Medical Center.